Myofascial pain syndrome (MPS) refers to pain and presumed inflammation in the body's soft tissues or muscles. Myofascial pain is a chronic, painful condition that affects the fascia (connective tissue that covers the muscles). Myofascial pain syndrome might involve either a single muscle or a muscle group. Myofascial pain syndrome typically occurs after a muscle has been contracted repetitively. This can be caused by repetitive motions used in jobs or hobbies or by stress-related muscle tension. Treatment options for myofascial pain syndrome include physical therapy and trigger point injections. Pain medications and relaxation techniques also can help.